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U.S. Legal & Legislative Sources

Where to go for the actual text behind U.S. pharmaceutical and medical device regulation — the statutes, the regulations, and the day-to-day rulemaking that amends them.

These sit below the agencies on the main Resources page in one sense and above them in another: FDA's authority comes from a statute, and its regulations are the specific rules FDA writes under that statute. For a plain-language walkthrough of how these pieces connect, see How the law actually fits together in the History of the FDA article.

A note on hierarchy: in order of legal authority, it runs statute (U.S. Code) → regulation (CFR) → agency guidance. A regulation has to be authorized by, and stay consistent with, the statute that created it.

This page covers the federal layer only. For how state, county, and city rules stack on top of it — using California and San Diego as a working example — see our Regulatory Compliance Hierarchy case study (PDF).

Trying to trace a requirement back to its source?

If you need help connecting a compliance question back to the statute or regulation behind it, I can help.

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